Bergeyella causing preterm births

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Transmission of infection from oral cavity

Recent studies have shown that Bergeyella , a rod shaped , gram negative pathogen found in the oral cavity of a pregnant woman can cause preterm births.

Contents

    Bergeyella zoohelcumis an uncommon zoonotic pathogen typically associated with cat or dog bites previously known as weeksella zooheculum have been…
    Research is still going on in this field

Bergeyella zoohelcumis an uncommon zoonotic pathogen typically associated with cat or dog bites previously known as weeksella zooheculum have been found to be a one of the cause of preterm deliveries.

Research is still going on in this field.

Periodontal gum disease is usually associated with preterm births.Bergeyella virosa was detected in the scrapings from mouth of a pregnant lady undergoing preterm labour.It is assumed that it might have travelled from a cut in the mouth cavity to the blood and then to the uterus.In the uterus it must have released prostaglandins due to infection hence triggering the uterine contractions.Scientists did a PCR ( polymerase chain reaction) test using 16 and 23SrRNA universally conserved primersand identified the bacteria.However the direct evidence for the transmission is still lacking.Onestrain,Bergeyellasp.clone AF14 was detected in uterus as well as mouth scrapings of a pregnant woman undergoing in preterm labour suggesting it the commonest cause of preterm births.Bergeyella or Weeksella virosa was found in 5 % normal women in urogenital tract and 15 % in reproductive age group.

Prevention

    Proper mouth wash , saline and betadine gargles.
    Scaling if periodontal disease is present.
    Use of Vitamin C so as to prevent gingivitis.
    Antibiotics like cefotaxime if gum disease is seen during pregnancy.

References

  • Botha, W. C., P. J. Jooste, and C. J. Hugo. 1998. The incidence of Weeksella- and Bergeyella-like bacteria in the food environment. J. Appl. Microbiol. 84:349-356
  • Yiping Han et al. Transmission of an uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth. Journal of Clinical Microbiology 2006; 44:1475-1483.
  • ------------------------------------------------------------------------------ Journal of Clinical Microbiology, April 2006, p. 1475-1483, Vol. 44, No. 4 0095-1137/06/$08.00+0 doi:10.1128/JCM.44.4.1475-1483.2006 Copyright © 2006, American Society for Microbiology. All Rights Reserved.

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